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https://scholar.google.com/citations?user=yAw2msMAAAAJ

Maternal & Child Nutrition

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https://scholar.google.com/citations?user=poyYJK0AAAAJ&hl=en&authuser=1

Epidemiology and Analytical toxicology

Highlights

• Arsenic exposure is dose-dependently associated with the risk of hyperglycemia.
• Females are found to be more susceptible to arsenic-related hyperglycemia.
• Low to moderate doses of water arsenic is related to the risk of hyperglycemia.

We found a significant inverse relationship between arsenic exposure and PChE activity in a human population in Bangladesh. This research demonstrates a novel exposure-response relationship between arsenic and PChE activity which may explain one of the biological mechanisms through which arsenic exerts its neuro-and hepatotoxicity in humans.

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Environmental Health Sciences, Metal toxicity especially on arsenic toxicity.

Widespread contamination of arsenic (As) has become a global public health concern. Exposure to As causes respiratory complications. Asthma, a major respiratory complication, is increasing worldwide. However, the effect of chronic As exposure on the risk of asthma remains to be clarified. This study aims to examine the associations between As exposure (water, hair and nail As) and the risk of asthma among 842 individuals exposed to a wide range of As concentrations through drinking water in Bangladesh. Subjects’ As exposure levels were measured with ICP-MS. Lung function was examined by a handheld spirometer. Characteristic features of asthma were evaluated by bronchodilator-mediated reversibility in airway obstruction and asthma-like symptoms through a structured questionnaire. Total serum immunoglobulin E (sIgE) levels were measured by immunoassay. As exposure metrics showed inverse associations with lung function measures (FEV1, FEV6, and FEV1/FEV6 ratio) and positive associations with the risks of airway obstruction (AO), reversible airway obstruction (RAO), and asthma-like symptoms. The majority of AO patients (70 of 97) were RAO with one or more characteristic symptoms of asthma. Intriguingly, subjects’ As exposure levels showed positive associations with total sIgE levels. Total sIgE in RAO patients was significantly (p < 0.001) higher than that in the control group. Thus the results revealed that chronic As exposure was associated with the risk of the characteristic features of asthma. Additionally the association between As exposure and subjects’ total sIgE levels and an elevated level of total sIgE in RAO group suggested that As exposure-related asthma might be allergic in nature.

Development of novel diet and therapeutic targets for the management of diabetes and cardiovascular diseases, Phytomedicine, Nutritional Biochemistry, and Food Science

https://www.researchgate.net/profile/Shaikh-Rahman-4/research

https://scholar.google.com/citations?user=PHm3fTAAAAAJ

Corresponding Author; Q1 Journal; Impact Factor: 1.893; H Index-18; Cite Score-1.66

IF-2.834 (Elsevier); Cite Score-4.5; H Index 18; (Q2 Journal)

SCI Journal; Impact factor: 0.43; Q4 Journal; H index-08

Q2 Journal; Impact Factor-2.6; H index-29

H Index 8, (Peer reviewed Journal)

Q1 journal; Impact factor:5.351, Cite score 9.4, and H index 11.

Q2 Journal; Impact Factor-2.6; H index-29

 IF-0.07; H Index 21 (Peer reviewed Journal)

Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

IF-0.21, SCI & Scopus journal

Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

IF-0.28, H Index 19 (Peer reviewed Journal)

Peer reviewed Journal

RG IF-0.37, Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

IF-0.43, H Index 8, Peer reviewed Journal

Peer reviewed Journal

Peer reviewed Journal

IF-0.47, H Index 17, (Peer reviewed Journal)

Peer reviewed Journal

IF-0.384, H Index 8, SCI & Scopus journal (Peer reviewed Journal)

Peer Reviewed Journal;  ISSN: 2469-7869 (Print); ISSN: 2469-8067 (Online)

IF-0.77; Cite Score-1.4;  H Index-10 (Scopus journal)

IF-3.5; Cite Score-1.8; H Index 9 (Peer-reviewed Journal)

Q1 journal; IF: 5.738; Cite Score: 5.8 H index: 73

 Q1 (Tier) journal; Impact Factor-6.0; Cite score-10.6, h-index-83.

Corresponding Author; Peer-reviewed; Scopus Journal (Elsevier).

Food safety, Heavy metal toxicity, Environmental pollution,

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Bioavailability of beta-carotene and other micro-nutrient, Micro-nutrient deficiency and its impact on public health nutrition

https://www.researchgate.net/profile/Md_Kamruzzaman3

https://scholar.google.com/citations?user=NANshP4AAAAJ&hl=en

Abstract

Abstract

Abstract

Adolescence is one of the most imperative stages of growth and development of human life cycle and nutritional imbalance during this stage is supposed to have prodigious impact on proper growth. The research aims to examine the impact of a nutrition education on nutritional status and knowledge of adolescent girls in rural and urban areas of south-west region of Khulna division of Bangladesh. Detailed questionnaire was used to collect socio-demographic and nutrition related data. Gomez classification and MUAC was used to classify the nutritional status of the respondent. Nutrition awareness and nutritional status of each of the respondent was assessed both before and after the nutrition education program. The 1st and 2nd survey showed a significant impact of nutrition education and improvement of nutritional status. Good hygienic practice was improved. Irregularities in food consumption and foods taboos were found to be reduced after nutrition education. Concept about nutrition and balanced diet was disseminated among 69.75% respondent which was only 19.25% before nutrition education program. Prevalence of mild and moderate malnutrition was decreased, whereas prevalence of normal nutritional status was increased from 15.75% to 44.5%. Nutrition education program was found to improve the nutritional status and nutrition knowledge of the respondent.

Abstract

Varieties of non-wheat cereal crops grow in Bangladesh, studies on the formulation and uses of composite flour are inconsistent and uncommon. Even though the effect of several other functional foods on glycemic profile has been studied, little is known about the effect of composite flour on glycemic profile in type-2 diabetic patients. A total of 30 type-2 diabetic patients were recruited and randomized into control (13 patients) and intervention group (17 patients). Before randomization, in 28 days run in period, base line anthropometric data and their habitual energy requirements were measured. After randomization, conventional wheat bread and bread from composite flour was fed to control and intervention group respectively for another 28 days. After each 7 days both fasted and after 2 hours postprandial blood glucose level were measured and statistically compared (p ≤ 0.05) with the respective group’s blood glucose level measured at the beginning of the intervention. A total of 6 patients were dropped out from the study. After each 7 days, in intervention group, postprandial blood glucose level was found significantly lowered (p ≤ 0.001), whereas fasted blood glucose level was only decreased significantly (p ≤ 0.005) after 28 days. There were no significant effects (p > 0.05) on fasted and postprandial glucose level in control group. The present study suggests that Bread made from composite flour with high fiber could be a novel and potentially effective method for glycemic control in type-2 diabetic patients compared with low fiber containing normal wheat bread.

Exclusive breast feeding means that the baby has no other food or drinks even 'dummy' or 'pacfier'. Human milk provides immunoglobulin and lactoferrin which protects the host gastrointestinal system from enterotoxigenic Escherichia coli a major cause of infant Diarrhoea. Secretory immunoglobulin-A is an important component of passive immunity in first weeks before endgenous immunoglobulin production begins. The current study showed that out 400 infants 15.5% were not anemic and possessed good health but 35% were moderately anemic, 43% were mild anemia and 6.5% were severely anemic. But this study showed alter result because child's health not only depend on breastfeeding but also many other factors such as weaning practice, vaccination, mother's awareness about sanitation and hygiene over all nutritional status of mother, usually they are anemic. After breastfeeding the second most critical factor is weaning practice that affects the child's health. Study showed around 59% family don’t know about weaning practice and their benefit and the proportion even higher in rural area (80.5%). The anemia prevalence (66%) was higher among 7-12 moths age group compared to below six months aged infants (34%). The prevalence of other two diseases was also higher among infant from rural area (40 and 57%). This higher prevalence of anemia, pneumonia and diarrhea among infant within 7 to 12 months and particularly in rural area could be explained by the hypothesis of inadequate knowledge and practice of weaning.

Abstract

Abstract

Abstract

Abstract

Postprandial glycemic control is an important target for optimal type 2 diabetes management, but is often difficult to achieve. The gastrointestinal tract plays a major role in modulating postprandial glycaemia in both health and diabetes. The various strategies that have been proposed to modulate gastrointestinal function, particularly by slowing gastric emptying and/or stimulating incretin hormone GLP-1, are summarized in this review.

Abstract

Dr. Mohammad Tanvir Sarwar has received his BSc , MSc in Applied Nutrition and Food Technology (ANFT) from Islamic University, Kushtia, Bangladesh in 2008 and 2009 respectively. He joined as a lecturer in the department of ANFT at Islamic University, Kushtia, Bangladesh in 2010. He achieved his PhD in Oral Molecular Biology in 2020 from Nagasaki University ,Japan. After finishing his PhD he worked as a visiting researcher in the department of Oral Molecular Biology at Nagasaki University, Japan in 2020. Dr. Tanvir has taught a numbers of courses, conducted a numbers of undergraduate and graduate examinations as well as supervised a numbers of MS students of the said department. He was involved in a numbers of national and international research projects as a principal and co-investigator. He has published a numbers of research articles in reputed international journals and has written a book chapter. He is now working as an Associate Professor at the Department of Applied Nutrition and Food Technology, Islamic University, Kushtia, Bangladesh.

Bacterial ecology, culturomics, bacterial protein isolation and purification

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https://scholar.google.com/citations?hl=en&user=Nw08loIAAAAJ

Multiple dipeptidyl-peptidases (DPPs) are present in the periplasmic space of Porphyromonas gingivalis, an asaccharolytic periodontopathic bacterium. Dipeptides produced by DPPs are presumed to be transported into the bacterial cells and metabolized to generate energy and cellular components. The present study aimed to identify a transporter responsible for dipeptide uptake in the bacterium. A real-time metabolic analysis demonstrated that P. gingivalis preferentially incorporated Gly-Xaa dipeptides, and then, single amino acids, tripeptides and longer oligopeptides to lesser extents. Heterologous expression of the P. gingivalis serine/threonine transporter (SstT; PGN_1460), oligopeptide transporter (Opt; PGN_1518) and proton-dependent oligopeptide transporter (Pot; PGN_0135) genes demonstrated that Escherichia coli expressing Pot exclusively incorporated Gly-Gly, while SstT managed Ser uptake and Opt was responsible for Gly-Gly-Gly uptake. Dipeptide uptake was significantly decreased in a P. gingivalis Δpot strain and further suppressed in a Δpot-Δopt double-deficient strain. In addition, the growth of the Δpot strain was markedly attenuated and the Δpot-Δopt strain scarcely grew, whereas the ΔsstT strain grew well almost like wild type. Consequently, these results demonstrate that predominant uptake of dipeptide in P. gingivalis is mostly managed by Pot. We thus propose that Pot is a potential therapeutic target of periodontal disease and P. gingivalis-related systemic diseases.

Prevotella intermedia, a Gram-negative anaerobic rod, is frequently observed in subgingival polymicrobial biofilms from adults with chronic periodontitis. Peptidases in periodontopathic bacteria are considered to function as etiological reagents. Prevotella intermedia OMA14 cells abundantly express an unidentified cysteine peptidase specific for Arg-4-methycoumaryl-7-amide (MCA). BAU17746 (locus tag, PIOMA14_I_1238) and BAU18827 (locus tag, PIOMA14_II_0322) emerged as candidates of this peptidase from the substrate specificity and sequence similarity with C69-family Streptococcus gordonii Arg-aminopeptidase. The recombinant form of the former solely exhibited hydrolyzing activity toward Arg-MCA, and BAU17746 possesses a 26.6% amino acid identity with the C69-family Lactobacillus helveticus dipeptidase A. It was found that BAU17746 as well as L. helveticus dipeptidase A was a P1-position Arg-specific dipeptidase A, although the L. helveticus entity, a representative of the C69 family, had been reported to be specific for Leu and Phe. The full-length form of BAU17746 was intramolecularly processed to a mature form carrying the N-terminus of Cys15. In conclusion, the marked Arg-MCA-hydrolyzing activity in Pre. intermedia was mediated by BAU17746 belonging to the C69-family dipeptidase A, in which the mature form carries an essential cysteine at the N-terminus.

The present study was carried out to analyze the antibiotic susceptibility of four pathogenic bacteria Escherichia coli, Enterobacter, Pseudomonas and Staphylococcus aureus respectively. Escherichia coli strains from 35 samples, Staphylococcusaureus strains from 35 samples, Enterobacter strains from 39 samples and Pseudomonas strains from 39 samples were isolated from 200 suspected infected individuals. Pure cultures of isolate were done by isolating single colony from the stored bacteria. Identification of strains were confirmed by various microscopic, colonial and biochemical tests. Finally identified four varieties of pathogenic strains Escherichia coli, Enterobacter, Pseudomonas and Staphylococcus aureus were subjected to the antibiotic sensitivity test by antibiotic disc diffusion method. Approximately 15 commonly used antibiotics were used in the tests. For this study it was observed that 94% of Escherichia coli were resistant to Cefixime, 86% to Cefuroxime Sodium, 77% to Ceftriaxone, 71% to Ceftazidime, 66% to Amoxycillin-Clavulanic acid and Ciprofloxacin, 63% to Levofloxacin, 57% to Doxycycline, 49% to Co-trimoxazole andonly 37% to Gentamicin. No Escherichia coli samples were found resistant against Meropenem having highest sensitivity (100%). Only 7 Escherichia coli samples were resistant to Amikacin having sensitivity 80% and 10 Escherichia coli samples were resistant to Nitrofurantion with the third highest sensitivity 71%. Staphylococcus aureus were observed to show maximum resistant (100%) towards Azithromycin, next to Ceftriaxone 74%, Ciprofloxacin and Oxacillin 71%, Co-trimoxazole 63%, Levofloxacin 57% and Amoxycillin-Clavulanic acid 49%. Only 5 Staphylococcus aureus samples were resistant to Gentamicin with a maximum sensitivity 86% and 7 Staphylococcus aureus samples were resistant to Amikacin having second highest sensitivity 80% and third highest sensitivity Cephalexin 63%. Enterobactor showedmaximum resistant towards Amoxycillin-Clavunic acid 100%, Cefixime 100%, Ceftadizime 100%, Ceftriaxone 95%, Amikacin 85%, Co-trimoxazole 79%, Ciprofloxacine 77%, Doxycyclin 72%, Gentamicin51%, Levofloxacin 46%, and Nitrofurantion 41%. There were found to be no Enterobacter Samples that resistant to Meropenem having highest sensitivity (100%). Only 16 Entarobacter samples were resistant to Nitrofurantion having second highest sensitivity59% and third highest sensitivity Levofloxacin 54%. Pseudomonus were observed to maximum resistant towards Amoxicillin 100%, Ceftazidime 100%, Cefixime 100%, Doxycycline 100%, Co-trimoxazole 100%, Ciprofloxacin 83%, Ceftriaxone 83%, Levofloxacin 83%, Nitrofurantion 83%, and Amikacin 67%. There were found to be no Pseudomonus Samples that resistant to Meropenem having highest sensitivity (100%). Only 13 Pseudomonus samples were resistant to Gentamicin with a maximumsensitivity 67%.

Traditional sun drying methods are widely used in Bangladesh to dry fish, though the quality is not satisfactory. The aim of this study was to assess the quality of solar tunnel dried Bombay duck and Siler pomfret, and to compare it with traditional sun dried Bombay duck and Silver pomfret. Raw fish samples of Bombay duck and Silver pomfret was collected and dried using solar tunnel dryer. The quality of the dried product was analyzed measuring moisture, protein, fat, ash, peroxide value and Total Volatile Base Nitrogen (TVB-N) content and analyzing water reconstitution properties. Traditional sun dried Bombay duck and Silver pomfret were also collected from different area, and the same measurement was also performed and compared with solar tunnel dried fish samples. Microbial quality was also analyzed using standard methods. Organoleptic quality of solar tunnel dried fish samples was found very well without any objectionable flavor and odor, compared with traditional sun dried fish samples. Moisture content was also observed (15.25 % in Bombay duck and 13.43 % in Silver pomfret) within the acceptable range. Protein content of solar dried fish samples was also found higher than that of traditional sun dried samples and water reconstitution power was also found better. Peroxide and TVB-N value of the solar tunnel dried studied samples were found within the normal limit of 10-20meq/kg of oil and up to 30 mg/100gm, respectively. Aerobic Plate Count was found lower, however Salmonella and Coliform was not found in both dried samples. The quality of solar tunnel dried Bombay duck and Silver pomfret samples were of excellent compared with samples dried by traditional sun drying method.

The antibacterial activity of chemically deacetylated chitin i.e. chitosan produced from shrimp shell. The antibacterial activity was tested against gram negative (Escherichia coli) bacteria, and gram positive (staphylococcus aureus) bacteria. To test the antibacterial activity institute of clinical laboratory standards (ICLS) approved dilution methods was used. The study was carried out by broth dilution method and used turbidity estimations to determine the growth characteristics of a bacterial culture with or without chitin or chitosan. Chitosan possess higher antibacterial activity against both types of bacteria, while chitin possess very lower activity. For staphylococcus aureus the average absorbance in every O.D value measured, staphylococcus aureus with chitin showed far higher absorbance than chitosan, indicates lower level of activity of chitin. After 32 hours of incubation s.aureus with medium absorbance was 1.15, while chitosan with s.aureus absorbance recorded 0.32, chitin with s.aureus recorded 0.733. Lower absorbance for chitosan containing E.Coli medium. At the peak point Medium and E.coli absorbance was 1.07, while chitosan with E.coli recorded 0.282 and chitin with E.coli absorbance was found 0.831. The ratio between medium E.coli and chitosan: medium and E.coli=0.26:1, and the ratio of medium S.aureus and chitosan : medium and S.aureus = 0.28:1, indicates G (+Ve) bacteria gives 0.02 times higher absorbance than G (-Ve) bacteria. The between chitin and chitosan, chitosan was found 2.2 times more active than chitin against S.aureus and 3.0 times more active than chitin against E.coli.

A cross-sectional study was conducted to determine nutritional status of pregnant women in different areas of Bangladesh by anthropometric and biochemical assessment. Measurement of body weight gain in different stages of pregnancy period was calculated as 20% and 14% severely malnourished, 54% and 30% moderately malnourished, 21% and 43% well nourished and 5% and 13% over malnourished ; hemoglobin (Hb) level was 16% and 19% severely anemic, 38% and 54% moderately anemic, 24% and 42% mildly anemic and 6% and 11% non-anemic; educational levels were 8% and 15% illiterate, 17% and 44% primary, 29% and 25% secondary, 10% and 39% under graduate and 2% and 11% post graduation of rural and urban pregnant women respectively. Monthly expenditure ≤ Tk.3000 to Tk.4000 food for rural and urban pregnant women were found and considered as important causes for nutritional status during pregnancy period. Beside these, early marriage, frequent birth, illiteracy, poverty, misconceptions, and lack of nutritional knowledge were follow up in this study period. The outcome showed that urban pregnant women were well nourished than rural pregnant women comparatively and also obesity was encountered as an indicator in urban pregnant women than rural.

Chitosan is a nitrogen containing polysaccharides that forms a semitransparent horny substance and is a principal constituent of the exoskeleton or outer covering of insects, crustaceans and arachnids. In recent years application of natural antimicrobials instead of conventional ones, due to their hazardous effects on health, has got serious attentions. On the basis of the results of different studies, chitosan, a natural bio-degradable and non-toxic biopolysaccharide derived from chitin, has potential to be used as a natural antimicrobial. Chitosan has exhibited high antimicrobial activity against a wide variety of pathogenic and spoilage microorganisms, including fungi, and Gram-positive and Gram-negative bacteria. In the present study the author prepared chitosan sample and used it as food preservative. Chitosan was prepared in two processes. Where one sample was prepared applying high temperature and pressure and other was without the application of high temperature and pressure. Chitosan applied as food preservative in orange juice and ginger paste. Microbial count was taken at 3, 8 and 16 days by MPN (Minimal Probable Number) method. Sub culture in selective media was done to distinguish coliform presence. The study work found that preservative used as chitosan sample-2 was found comparatively acceptable. By the study the shelf life of ginger and juice was observed for organoleptic properties which were acceptable. The experiment was done in room temperature. The ginger paste was found to be acceptable on day 8 as bacterial count was found 1.4×106 and fungal count 7.5× 105 . The orange juice was found to be acceptable on day 8 as bacterial count was found 5.5× l04. Where at same day fungal count 2.6×105. Further investigation of health affect of chitosan preserved food is required in future. Chitosan has a great impact to eliminate chemical preservative as it works efficiently as preservative.

Public health

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https://scholar.google.com/citations?user=2YriqLoAAAAJ&hl=en